I have worked with many Linux GUI library's. The easiest one to work with is Gtk+ in my opinion. It is easy to start with and you can quickly get an app going with it especially if you combine it with the glade gui builder. The one that produces the best looking apps is Qt (again imo.) You can combine it with QtDesigner or KDevelop to have a full IDE environment to work with it in as well as drag and drop gui building.
So having gotten those out of the way... wxWidgets is the best out there at the moment. I think it is the best no matter what platform you are developing on because it's portability is simply incredible. wxWidgets isn't just a GUI library but a portability framework as quoted from the wxWidget's founders book
Cross-Platform GUI Programming With wxWidgetsQUOTE
wxWidgets is a programmer's toolkit for writing desktop or mobile applications with graphical user interfaces (GUIs). It is a framework, in the sense that it does a lot of the housekeeping work and provides default application behavior.
wxWidgets contains it's own functionality for a lot of the things that are troublesome in porting such as launching external applications, file io, sockets, threads, and many other necessary tasks. It is completely class based and the API structure makes sense. It is a great toolkit to work with. When you compile your app in Linux it will look like it belongs in Linux. When you compile it in OS X, Windows, or any one of the many platforms supported it will look native (and most of the time the widgets are the native ones.) If you use Code::Blocks and wxSmith or wxFormBuilder you will have a completely cross-platform environment to work in so that you are looking at the same application and working with the same project files whether you are working in Windows or Linux. I have been writing Linux apps and porting them to other platforms for many years and I have only been looking at wxWidgets and Code::Blocks as a multi-platform solution for the last year. I am very excited about it.
So now that I have gotten my spill out of the way... I would recommend wWidgets.